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MB

Mkt Cap

$2.38B

Volume

682.90K

Next Earnings

November 5th

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MB

MBXMBX Biosciences, Inc. Common Stock

MBX

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MB

Mkt Cap

$2.39B

Volume

682.90K

Next Earnings

November 5th

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MBX Biosciences Announces One-Year Data Demonstrating Sustained Benefit of Once-Weekly Canvuparatide as a Potential PTH Replacement Therapy in Chronic HypoparathyroidismMBX Biosciences announced positive one-year data from its open-label extension study of canvuparatide, a once-weekly PTH replacement therapy for chronic hypoparathyroidism. The drug maintained a 57% responder rate at one year with a 90% retention rate, demonstrated sustained benefits in calcium homeostasis, kidney function, and bone metabolism, and showed no new safety signals. The company remains on track to initiate Phase 3 pivotal trials in Q3 2026.GlobeNewswire Inc. · Jun 12, 2026

AstraZeneca's Rare Disease Drug Shows Reduced Dependence On Calcium SupplementsAstraZeneca announced that its investigational drug eneboparatide (AZP-3601) met the primary endpoint in the Phase 3 CALYPSO trial for chronic hypoparathyroidism. The therapy demonstrated that 31.1% of patients achieved normal calcium levels and independence from vitamin D and calcium supplements at week 24, compared to 5.9% in the placebo group. The drug was generally well-tolerated, with benefits maintained through 52 weeks, though immunogenicity was observed in some patients.Benzinga · May 12, 2026

MBX Biosciences Provides Obesity Portfolio Update Including Initial Phase 1 Data for MBX 4291 Supporting Potential for Once-Monthly DosingMBX Biosciences announced preliminary Phase 1 data for MBX 4291, a GLP-1/GIP co-agonist prodrug showing 7% mean weight loss at 8 weeks with good tolerability and potential for once-monthly dosing. The company also nominated MBX 5765, a novel four-agonist candidate for obesity, and achieved proof of concept for imapextide in post-bariatric hypoglycemia, though will not pursue further Phase 2b development of the latter to prioritize resources.GlobeNewswire Inc. · May 11, 2026

MBX Biosciences Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)MBX Biosciences announced the appointment of Karen Basbaum as Chief Business Officer and issued her an equity inducement award of 130,000 non-qualified stock options with an exercise price of $32.29 per share. The options vest over four years with a 10-year term, approved by the board as a material inducement for her employment.GlobeNewswire Inc. · Apr 3, 2026

This Biotech Fund Just Dumped $14.8 Million in MBX Biosciences — Right Before Key 2026 MilestonesMPM BioImpact sold its entire 1.3 million share stake in MBX Biosciences, worth $14.8 million, during Q3 2025, just before the company's pivotal clinical trials and potential key milestones in 2026.The Motley Fool · Dec 3, 2025

MBX Biosciences Announces Pricing of Upsized Public OfferingMBX Biosciences is conducting a public offering of 11,108,055 shares at $18.00 per share, expecting to raise approximately $199.9 million to support its precision peptide therapy development for endocrine and metabolic disorders.GlobeNewswire Inc. · Sep 25, 2025

MBX Biosciences Announces Proposed Public OfferingMBX Biosciences has filed a registration statement for a proposed public offering of 10 million common stock shares, with an additional option for underwriters to purchase 1.5 million shares. The offering is subject to market conditions and has major investment banks as joint book-running managers.Benzinga · Sep 22, 2025

MBX Biosciences Announces Once-Weekly Canvuparatide Achieved Primary Endpoint in Phase 2 Trial with 63% Responder Rate at 12 Weeks; 79% Responder Rate at 6 Months in Open-Label ExtensionMBX Biosciences reported successful Phase 2 trial results for canvuparatide, a potential once-weekly treatment for hypoparathyroidism, with 63% responder rate at 12 weeks and 79% at 6 months, with plans to initiate Phase 3 trials in 2026.GlobeNewswire Inc. · Sep 22, 2025

MBX Biosciences to Present at the American Diabetes Association 85th Scientific SessionsMBX Biosciences, a clinical-stage biopharmaceutical company, announced presentations at the American Diabetes Association's 85th Scientific Sessions. The presentations will focus on the safety, pharmacokinetics, and pharmacodynamics of their investigational drug MBX 1416, a GLP-1 receptor antagonist, for the treatment of post-bariatric hypoglycemia.GlobeNewswire Inc. · Jun 10, 2025

MBX Biosciences to Participate in Upcoming November Investor ConferencesMBX Biosciences, a clinical-stage biopharmaceutical company, announced its participation in upcoming investor conferences, including the Guggenheim Inaugural Healthcare Innovation Conference, Stifel 2024 Healthcare Conference, and Jefferies London Healthcare Conference.GlobeNewswire Inc. · Oct 28, 2024

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