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BB
BridgeBio Pharma, Inc. Common Stock
BBIO
Mkt Cap
$12.98B
Volume
1.79M
Next Earnings
November 4th
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BB
BBIO
BB
BridgeBio Pharma, Inc. Common Stock
BBIO
News
·
Acoramidis Associated with Significantly Improved Clinical Outcomes Versus Tafamidis in ATTR-CM in an Independent, Real-World Study of U.S. Electronic Health Records
Mkt Cap
$12.98B
Volume
1.79M
Next Earnings
November 4th
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Earnings
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Acoramidis Associated with Significantly Improved Clinical Outcomes Versus Tafamidis in ATTR-CM in an Independent, Real-World Study of U.S. Electronic Health Records
An independent real-world study of 2,684 ATTR-CM patients from U.S. electronic health records found that acoramidis was associated with an 18% lower risk of death, hospitalization, atrial fibrillation, and diuretic intensification compared to tafamidis. Acoramidis showed 27% lower risk of cardiovascular and heart failure hospitalizations. These findings replicate earlier comparative effectiveness analyses and support acoramidis as a preferred stabilizer treatment option.
GlobeNewswire Inc. · Oct 11, 2026
Encaleret Increased Bone Turnover and Improved Participant-Reported Symptoms in the Phase 3 CALIBRATE Trial in ADH1
BridgeBio announced positive Phase 3 CALIBRATE trial results for encaleret in autosomal dominant hypocalcemia type 1 (ADH1), showing 91% of participants achieved normal PTH levels compared to 0% on standard care, with 100% reporting symptom improvements versus 46% on conventional therapy. The FDA accepted the NDA with Priority Review (PDUFA date May 8, 2027), and the company initiated the Phase 3 RECLAIM-HP trial for chronic hypoparathyroidism.
GlobeNewswire Inc. · Oct 11, 2026
FDA Grants Priority Review to BridgeBio's Dwarfism Drug Filing
BridgeBio Pharma announced FDA acceptance of its regulatory filing for infigratinib, an oral drug to treat achondroplasia in children, with priority review and a decision expected by February 4, 2027. The drug demonstrated 2.1 cm/year greater height growth than placebo in Phase III trials. If approved, it would be the first oral therapy for achondroplasia, differentiating it from injectable competitors. BridgeBio also has two other near-term regulatory catalysts (BBP-418 and encaleret) that could diversify its revenue beyond its current marketed product Attruby.
Zacks Investment Research · Oct 7, 2026
BioMarin Stops Voxzogo Development for Noonan Syndrome
BioMarin Pharmaceutical announced it is discontinuing development of Voxzogo for Noonan syndrome due to study feasibility and treatment landscape concerns, though not due to safety or efficacy issues. Despite this setback, Voxzogo generated $472 million in first-half 2026 sales (up 9% YoY) and is on track to achieve blockbuster status with expected 2026 sales of $1.00-$1.05 billion. The drug faces increasing competition from Ascendis Pharma's Yuviwel and BridgeBio's infigratinib, though BioMarin secured a royalty-bearing settlement with Ascendis.
Zacks Investment Research · Sep 16, 2026
How BioMarin Turned a Competitive Threat Into a Royalty-Bearing Asset
BioMarin settled a patent dispute with Ascendis Pharma over the achondroplasia drug Yuviwel, converting a competitive threat into a royalty stream. Under the agreement, BioMarin will receive 20% royalties on U.S. Yuviwel sales and 18% in the EU, Brazil, and South Korea through May 2030. While this monetizes competition, BioMarin still faces market pressure from Yuviwel and potential future competitors like BridgeBio's infigratinib.
Zacks Investment Research · Sep 3, 2026
BridgeBio Announces Agreement with U.S. Government to Improve Affordability and Access to Critical Medicines for Americans
BridgeBio Pharma has entered into a voluntary agreement with the U.S. government to expand Medicaid access to its marketed medicine Attruby and lower drug costs for American patients. The agreement includes expanded state Medicaid access via the GENEROUS Model and maintains the company's ForgingBridges patient assistance program. BridgeBio expects not to be subject to future pricing mandates under this arrangement.
GlobeNewswire Inc. · Aug 31, 2026
BridgeBio Stock Has Soared 29% in Just 3 Months. Here's Why Wall Street Thinks It Could Go Even Higher.
BridgeBio Pharma's stock has surged 29% in three months, driven by strong performance of its FDA-approved heart medication Attruby, which saw sales more than triple year-over-year to $222 million in Q2. With 16 out of 17 analysts recommending a buy and three promising drugs in late-stage development under FDA review, Wall Street believes the stock has further upside potential despite the company remaining unprofitable.
The Motley Fool · Aug 14, 2026
Transthyretin Amyloidosis Treatment Market Size to Reach USD 35.10 Billion by 2035, Growing at a 14.64% CAGR | SNS Insider
The transthyretin amyloidosis treatment market is projected to grow from USD 8.95 billion in 2025 to USD 35.10 billion by 2035 at a 14.64% CAGR. Growth is driven by increased ATTR-CM diagnosis rates, FDA approvals of gene-silencing therapies like vutrisiran and acoramidis, improved diagnostic imaging, and expanding pipeline therapies. North America dominates with 46% market share, while Asia Pacific is the fastest-growing region.
GlobeNewswire Inc. · Jul 7, 2026
Wall Street Thinks This Biotech Stock Can Soar 45%. Here's Why Analysts Are Right.
Alnylam Pharmaceuticals has gained strong analyst support with 21 of 29 analysts rating it as buy or strong buy, with an average price target of $436 (45% upside). The company is transitioning from a clinical biotech to a profitable commercial powerhouse, with Q1 product revenue surging 121% year-over-year to $1.04 billion, driven by its ATTR franchise. The company's pipeline is expanding into mainstream markets like cardiomyopathy and hypertension, supported by a unique RNAi delivery platform that creates a competitive moat. However, the stock trades at a high valuation of 75x trailing earnings, with risks from competitive pricing pressure.
The Motley Fool · Jul 2, 2026
BridgeBio Raises $1 Billion in Preferred Equity to Accelerate Present and Upcoming Launches
BridgeBio Pharma announced a $1 billion preferred equity investment led by Sixth Street ($800M) and HealthCare Royalty ($133.9M). The Series A Cumulative Convertible Preferred Stock features a 7% dividend and conversion price of $137.79 per share (100%+ premium to 30-day VWAP). The capital strengthens BridgeBio's balance sheet as it prepares for potential launches of three blockbuster drugs: BBP-418 for LGMD2I/R9, encaleret for ADH1, and infigratinib for achondroplasia, while Attruby continues to grow as a multi-billion-dollar drug.
GlobeNewswire Inc. · Jul 1, 2026
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