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BioCryst Pharmaceuticals Inc
As of May 30, 2026 at 24:05 UTC
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About BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc is a biotechnology company involved mainly in the research and development of novel small-molecule drugs, to block key enzymes involved in infectious and inflammatory diseases. Biocryst's research is based on multiple scientific disciplines like biology, computer modeling, and medicinal chemistry. Its products and candidates target the following therapeutic areas: acute uncomplicated influenza; uncomplicated seasonal influenza; hereditary angioedema; filoviruses, including the Ebola and Marburg viruses; and oncology.
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Latest News
5 articlesBioCryst Pharmaceuticals reported Q1 2026 ORLADEYO net revenue of $148.3 million, up 11% year-over-year. The company announced a licensing agreement with Neopharmed Gentili for European commercial rights to navenibart, receiving $70 million upfront and up to $275 million in milestone payments. Patient enrollment in the navenibart pivotal study remains on track for completion by end of June 2026, with US regulatory filing expected by end of 2027. The company maintained its full-year 2026 revenue guidance of $625-645 million for ORLADEYO.
BioCryst Pharmaceuticals granted an Irish affiliate of Neopharmed Gentili exclusive European rights to commercialize navenibart for hereditary angioedema. BioCryst will receive $70M upfront, up to $275M in future milestone payments, and 18-30% royalties on sales. The agreement builds on their prior ORLADEYO business sale and supports BioCryst's strategy to focus on U.S. commercialization while strengthening its financial position.
BioCryst Pharmaceuticals announced the appointment of Dr. Sandeep M. Menon as Chief Research and Development Officer. Dr. Menon brings extensive experience from leadership roles at Alnylam Pharmaceuticals and Pfizer, where he oversaw clinical development of multiple therapies including AMVUTTRA and PAXLOVID. The appointment comes as BioCryst advances its navenibart program toward potential FDA approval and builds on the commercial success of ORLADEYO and the recent acquisition of Astria Therapeutics.
BioCryst Pharmaceuticals announced that its compensation committee granted restricted stock units (RSUs) covering 65,850 shares of common stock to six newly-hired employees as inducement grants. The RSUs vest in four equal annual installments beginning one year from the grant date of March 2, 2026, subject to continued employment.
BioCryst Pharmaceuticals achieved full-year profitability for the first time in company history in 2025, with ORLADEYO net revenue reaching $601.8 million (+38% y-o-y). The company received FDA approval for ORLADEYO oral pellets for children ages 2-11 and completed the acquisition of Astria Therapeutics to expand its HAE portfolio with navenibart. BioCryst maintained 2026 ORLADEYO revenue guidance of $625-645 million and reported record operating profit despite selling its European ORLADEYO business.