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ALX Oncology Holdings Inc. Common Stock
As of May 30, 2026 at 24:05 UTC
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About ALX Oncology Holdings Inc. Common Stock
ALX Oncology Holdings Inc is a clinical-stage immuno-oncology company focused on helping patients fight cancer by developing a pipeline of product candidates based on expertise in protein engineering and oncology led by the CD47 blocker, evorpacept, currently in phase 1 and 2 clinical trials. Cancer cells leverage CD47, a cell surface protein, as a don't eat me signal to evade detection by the immune system. It is developing a next-generation checkpoint inhibitor designed to have a high affinity for CD47 and to avoid the limitations caused by hematologic toxicities inherent in other CD47 blocking approaches.
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Latest News
5 articlesALX Oncology reported Q4 2025 financial results with improved net losses and announced strong clinical progress for its lead candidates evorpacept and ALX2004. The company validated CD47 as a predictive biomarker for evorpacept response in cancer trials, completed a $150 million equity offering extending cash runway through H1 2028, and appointed Barbara Klencke as permanent Chief Medical Officer. Multiple clinical milestones are anticipated over the next 12-18 months.
ALX Oncology announced its participation in the 44th Annual J.P. Morgan Healthcare Conference, with CEO Jason Lettmann and CMO Barbara Klencke delivering a corporate presentation on January 15, 2026. The clinical-stage biotech company is advancing evorpacept, a CD47-inhibitor being evaluated across multiple cancer indications, and ALX2004, an EGFR-targeted antibody-drug conjugate in Phase 1 trials.
ALX Oncology reported impressive results from a Phase 2 trial combining evorpacept with rituximab and lenalidomide in treating indolent non-Hodgkin lymphoma, achieving a 92% complete response rate and 100% overall response rate.